List of Completed research

Study Title

Completed

Status

ASPAC – The Asian-Pacific Study on Coronary Heart Disease Risk Factor Intervention ( Coronary Heart Disease Risk Factors in Patients with Acute Coronary Syndromes in the Asia Pacific Region )

2000

Completed

CHARM Study – Candesartan Cilexetil in Heart Failure Assessment of Reduction in Mortality and Morbidity

2002

Completed

ASIA PACIFIC MINICROWN Registry

2002

Completed

A – Z Study – AGGRASTAT to ZOCOR

2004

Completed

DECODE STUDY – A Randomized Study with the Sirolimus-Eluting BX Velocity Balloon-Expandable Stent in the Treatment of Diabetic Patients with Native Coronary Artery Lesions

2004

Completed

ACUTE II – An Randomized, Parallel, Double Blind Safety Study of Enoxaparin VS Unfractopmated Heparin in Tirofiban and Aspirin Treated.

2004

Completed

OVERTURE – Omapatrilat versus Enalapril Randomized Trial of Utility in Reducing Events.

2004

Completed

MICHAELANGELO OASIS 5 – UA / NSTEMI – An international Randomised Double-Blind Study Evaluating the Efficacy and Safety of Fondaparinux versus Enoxaparin In the Acute Treatment of Unstable Angina / Non ST Segment Elevation MI Acute Coronary Syndromes

2005

Completed

MICHAELANGELO OASIS – 6 (STEMI) – An International Randomized Study Evaluating the Efficacy and Safety of Fondaparinux Sodium versus Control Therapy and Glucose-insulin-potassiumInfusion versus Control in Broad Range of Patients with ST Segment Elevation

2005

Completed

ExTRACT – Timi 25 ; A Randomized Double-Blind, Double-Dummy, Parallel Group, Multinational, Clinical Study to Evaluate the Efficacy and Safety of Enoxaparin Versus Unfractionated Heparin in Patients with Acute ST Segment Elevation Myocardial Infarction

2005

Completed

RIVIERA – Registry on Intravenous Anticoagulation in the Elective and Primary Real World of Angioplasty.

2005

Completed

DISCOVERY Trial – An Open-Label Randomised, Multi-Centre, Phase Iiib/IV, Parallel Group Study to Compare the Efficacy and Safety of Rosuvastatin and Atorvastatin in Subjects with Type Iia and Iib Hypercholesterolaemia

2005

Completed

ACCORD Registry – Acute Coronary Syndromes Descriptive Study ACCORD Registry. Evaluation of Compliance with Existing Guideline in Patients with Acute Coronary Syndromes (Unstable Angina and Non-ST elevation Myocardial Infarction.

2005

Completed

Early ACS Trial – Early Glycoprotein IIb/IIIa Inhibition in Non ST Segment Elevation Acute Coronary Syndrome : A randomised, Placebo-Controlled Trial Evaluating the Clinical Benefits of Early Front-loaded Eptifibatide (the cont… refer the progress)

2007

Completed

ADAGIO – A Randomized ,Double-Blind,Two Arms Placebo-Controlled,Parallel,Multicenter Study of Rimonabant 20mg Once Daily in the Treatment of Atherogenic Dyslipidemia in Abdominally Obese Patients.

2007

Completed

E-5 registry – Endeavor Five Registry

2007

Completed

e-Healing Registry – Healthy Endothelial Accelerated Lining Inhibits Neointimal Growth Registry

2007

Completed

TRANSCEND – Telmisartan Randomized Assessment Study in ACE Intolerant

2008

Completed

ONTARGET – Ongoing Telmisartan Alone In Combination With Ramipril Global End Point Trial

2008

Completed

REACH Registry – An International Prospective Observation Registry in Subjects at Risk of Atherothrombotic Events.

2008

Completed

POST MI Study – Open-Labeled Multicentre Study to Assess The Efficacy of Switching to a combination tablet Ezetimibe / Simvastatin 10 mg / 40 mg, Compared to Doubling the Dose of Statin in Patients Hospitalised with a Coronary Event.

2008

Completed

OLYMPIC Registry – Global Taxus Libert’e Registry Programme to Support Worlwide Commercialisation

2008

Completed

INSPIRE ME / IAA

2008

Completed

ATHENA – A Placebo-Controlled, Double Blind, Parallel Arm Trial to Assess the Efficacy of Dronedarone 400 mg Bid for the Prevention of Cardiovascular Hospitalization or Death From Any Cause in Patients with Atrial Fibrillation/Atrial Flutter (AF/AL).

2008

Completed

IDMPS – International Diabetic Management Practice Study

2008

Completed

HEAAL – A Multicenter,Double-Blind Randomized,Parallel Group Study to Evaluate the Effects of Two Different Doses of Losartan on Morbidity and Mortality in Patients with Symptomatic Heart Failure Intolerant of ACE Inhibitor Treatment.

2009

Completed

ACTIVE – Atrial Fibrillation Clopidogrel Trial with Irbesatan for Prevention of Cardiovascular Events

2009

Completed

RE-LY STUDY – Randomized Evaluation of Long Term Anticoagulant Therapy (RE-LY) Comparing the Efficacy and Safety of Two Blinded Doses of Dabigatran Etexilate with Open Label Warfarin for the Prevention of Stroke and Systemic Embolism in Patients with

2009

Completed

PLATO – A Study of Platelet Inhibition and Patient Outcomes;A Randomized,Double-Blind,Parallel Group,Phase 3,Efficacy and Safety of AZD6140 Compared with Clopidogrel for Prevention of Vascular Events in Patients with Non-ST or ST Elevation Acute Coronary Syndrome (ACS)

2009

Completed

CRESCENDO – Randomized, Multinational, Multicenter, Double-Blind Placebo-Controlled, Two Arm Parallel Group Trial of rimonabant 20 mg OD for Reducing the Risk of Major Cardiovascular Events in Abdominally Obese Patients with Clustering Risk Factors.

2009

Completed

SEPIA ACS1 – A Randomised, Double-Blind, Triple-Dummy, Dose-Ranging Study, Including an Active Control of Unfractionated Heparin and Eptifibatide, (Cont. Below)

2009

Completed

CURRENT/OASIS 7 – Randomized, Multinational, Double-Blind Study, Comparing a High Loading Dose Regimen of Clopidogrel Versus Standard Dose in Patients With Unstable Angina or Non-ST Segment Elevation Myocardial Infarction Managed with an Early Invasive Strategy

2009

Completed

IMAGE IoproMide (Ultravist®) – To Gain further Information on Tolerability and Safety in X-Ray Examination

2009

Completed

ASCEND-HF – Acute Study of Clinical Effectiveness of Nesiritide in Subjects with Decompensated Heart Failure

2009

Completed

CLARINET – International Randomized Double Blind Study Evaluating the Efficacy and Safety of Clopidogrel 0.2 mg/kg Once Daily Versus Placebo

2009

Completed

DOT-HF – Diagnostic Outcome Trial in Heart Failure

2009

Completed

S9 Stent – Physician Assessment of the Medtronic S9 Bare Metal Stent Utilized for Treatment of Coronary Occlusive Disease

2010

Completed

PRIMULA – Prevalence, Treatment Patterns & Resource use in Patient with Mixed Dyslipidemia Using Lipid Lowering Agents

2010

Completed

SPIRIT V – A Clinical Evaluation of the XIENCETM V Everolimus Eluting Coronary Stent System in the Treatment of Patients with Native Coronary Artery Lesions.

2010

Completed

SPIRIT V (Diabetic) – A Clinical Evaluation of the XIENCETM V Everolimus Eluting Coronary Stent System in the Treatment of Patients with Native Coronary Artery Lesions. (Diabetic Patient)

2010

Completed

Rocket AF – A Prospective, Randomized, Double-Blind, Double-Dummy, Parallel-Group, Multicentre, Event-Driven, Non-Inferiority Study Comparing the Efficacy and Safety of Once-Daily Oral Rivaroxaban (Bay 597939) with Adjusted-Dose Oral Warfarin for ths Prevention of Stroke and Non-Central Nervous System Systemic Embolism in Subjects with Non-Valvular Atrial Fibrillation (Protocol No: 150-CL-030)

2010

Completed

Q-SYMBIO – Coenzyme Q10 s Adjunctive Treatment of Chronic Heart Failure.

2010

Completed

CARE II – A Prospective, Randomized, Multicenter Study to Evaluate the Safety, Efficacy, and Performance of the CardioMind Coronary Stent Systems for Treatment of Stenotic Lesions

2010

Completed

PLATINUM QCA – A Prospective, Multi-center Trial to Assess an Everolimus-Eluting Coronary Stent System – PROMUS ELEMENT TM

2010

Completed

TRACER – A Multicenter ,Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of SCH 530348 in Addition to Standard of Care in Subjects With Coronary Syndrome: Thrombin Receptor Antagonist for Clinical Event Reduction in Acute Coronary Syndrome

2010

Completed

ASSERT – Device-Detected Atrial High RateEpisodes-Asymptomatic AF & Stroke Evaluation in Pacemaker Patient &the AF Reduction Atrial Pacing Trial

2010

Completed

SHIFT – Effects of Ivabradine on Cardiovascular Events in Patients with Moderate to Severe Chronic Heart Failure and Left Ventricular Systolic Dysfunction. A Three-Year Randomised Double-Blind Placebo-Controlled International Multicentre Study

2010

Completed

REVATIO – Multinational, Multicentre, Randomized,Parallel Group,Double-Blind Study to Assess the Efficacy and Safety of 1mg , 5 mg and 20 mg TID of Oral Sildenafil in the Treatment of Subjects Aged 18 Years and Over with Pulmonary Arterial Hypertension

2011

Completed

SAFE – Septal Pacing for Atrial Fibrillation Suppression Evaluation Atherothrombotic Events

2011

Completed

PACE – Pacing to Avoid Cardiac Enlargement

2011

Completed

E-Select

2011

Completed

Record AF-AP – Registry on Cardiac Rhythm Disorder: An International ,Observational, Prospective Survey Assessing the Control of Atrial Fibrillation in Asia Pacific.

2011

Completed

Medtronic Attain Success Clinical Trial

2011

Completed

TRA2P – A Multicenter, Randomized, Double-blind,Placebo-controlled Study to Evaluate the Safety and Efficacy of SCH 530348 in Addition to Standard of Care in Subjects With a History of Atherosclerotic Disease: Thrombin Receptor Antagonist in Secondary Prevention of Atherothrombotic Ischemic Events ( TRA 2°P –TIMI 50) ( Protocol Number.P04737)

2012

Completed

SERAPHIN ( DOUBLE-BLIND) – Study with Endothelin Receptor Antagonist in Pulmonary Arterial Hypertension to Improve Clinical Outcome

2012

Completed

The PEPCAD IV DM Pilot Study – Paclitaxel-Eluting Balloon Angioplasty and Cobalt-Chromium Stents Versus Conventional Angioplasty and Paclitaxel-Eluting Stents in the Treatment of Native Coronary Artery Stenoses of Diabetic Patients.

2012

Completed

RELY ABLE – Multi-Centre Long Term Open Label Follow-Up Treatment of Patients with Non-Valvular Atrial Fibrillation Who Have Been Previously Treated with Dabigatran or Warfarin in the RE-LY Trial and a Cluster Randomised Trial to Assess the Effect of a Knowledge Translation Intervation on the Patient’s Prognosis,Cardiovascular Risk Profile and Quality of Atrial Fibrillation Management , As Compared to General Information on Best Evidence Based Medicine

2012

Completed

TRILOGY ACS – Lilly Protocol H7T-MC_TABY – A Comparison of Prasugrel and Clopidogrel in Subjects with Unstable Angina / NSTEMI Acute Coronary Syndrome who are Medically Manage.

2012

Completed

V710 – A Randomized, Multicenter, Double-Blind, Group-Sequential Study to Evaluate the Efficacy, Immunogenicity, and Safety of a Single Dose of Merck 0657nl Staphylococcus Aureus Vaccine (V710) in Adult Patients Schedule for Cardiothoracic Surgery.

2012

Completed

EXAMINE – A Multicenter,Randomized,Double-Blind,Placebo-Controlled Study to Evaluate Cardiovascular Outcomes Following Treatment with Alogliptin in Addition to Standard of Care in Subjects with Type 2 Diabetes and Acute Coronary Syndrome.

2013

Completed

CONTRAST – Combined N-Acetylcysteine and Bicarbonate in PCI To Reduce Adverse Side Effect of Contrast

2013

Completed

IMPROVE IT – A Multicenter Double-Blind Randomized Study to Establish the Clinical Benefit & Safety of Vytorin (Ezetimibe /Simvastatin Tab) vs Simvastatin Monotherapy in High Risk Subjects Presenting with ACS (Improved reduction of outcomes: Vytorin Efficacy Inter. Trial)

2014

Completed

PROTECT – Patient Related Outcomes with Endeavor Versus Cypher Stenting Trial

2014

Completed

SIGNIFY – Study (Effects of Ivabradine in Patients with Stable Coronary Artery Disease without Clinical Heart Failure).

2014

Completed

Pain Free SST CLINICAL STUDY

2014

Completed

IVORY – Ingenio Device Algorithm Study

2014

Completed

MIRACLE EF TRIAL

2014

Completed

TRICS II – Transfusion Requirements in Cardiac Surgery

2014

Completed

ALECARDIO – Study (T2D) Cardiovascular Outcomes Study to Evaluate the Potential of Aleglitazar to Reduce Cardiovascular Risk in Patients with A Recent Acute Coronary Syndrome (ACS) Event and Type 2 Diabetes Mellitus

2014

Completed

PLATINUM WH – A Prospective , Randomized, Multicenter Trial to Assess an Everolimus-Eluting Coronary Stent S( PROMUS ElementTM) for the Treatment of Up to Two De Novo Coronary Artery Lesions

2015

Completed

GRIPHON Study – A Multicenter, Double-Blind, Placebo-Controlled Phase 3 Study to Demonstrate the Efficacy and Safety of ACT-293987 in Patients with Pulmonary Arterial Hypertension

2015

Completed

SIMPLE – Shockless Implant Evaluation. A Prospective Randomized Clinical Study

2015

Completed

Attain Performa – Medtronic Attain® PerformaTM Quadripolar Lead Clinical Study

2015

Completed

Model 20066 LV Lead Study

2015

Completed

ABSORB FIRST REGISTRY

2015

Completed

CL3-16257-098 – Safety of Oral Chronic Administration of Ivabradine Modified Release Formulation Compared to Ivabradine Immediate Release Formulation in Patients with Chronic Heart Failure and Left Ventricular Systolic Dysfunction. A 6 to 12 months Randomised Double Blind Parallel Groups Multicentre Study.

2015

Completed

MultiSENSE – Multisensor Chronic Evaluations in Ambulatory Heart Failure Patients

2015

Completed

ABSORB EXTEND – A Continuation in the Clinical Evaluation of the Abbott Vascular Everolimus-Eluting Bioresorbable Vascular Scaffold in the Treatment of Subjects with De Novo Native Coronary Artery Lesions

2015

Completed

CLARIFY – Prospective Observational Longitudinal Registry of Patients with Stable Coronary Artery Disease

2015

Completed

CRT MPP – More Response on Cardiac Resynchronization Therapy (CRT) with MultiPoint Pacing (MPP)

2015

Completed

STICH – Surgical Treatment for Ischemic Heart Failure

2016

Completed

REMEDEE – A Prospective ,Randomized Study to Evaluate the Safety and Effectiveness of an AbluMinal Sirolimus CoatED Bio-Engineered StEnt ( Combo Bio-Engineered Sirolimus Eluting Stent) Compared with TAXUSR LiberteR Stent Control Arm for Treatment of Stenotic Lesions in Native Coronary Arteries

2016

Completed

RESOLUTE Asia – A Prospective, Multicenter, Non-randomized Study, Evaluation of the Endeavor Resolute Zotarolimus-Eluting Coronary Stent System in a Patient Population with Long Lesion(s) and/or Dual Vessels in Asia

2016

Completed

A Randomized , Multicenter Study to Evaluate Cardiovascular Outcomes with ITCA 650 in patients Treated with standard of Care for Type 2 Diabetes

2016

Completed

MICRA Transcatheter Pacing Study

2016

Completed

Leaders Free – A Prospective Randomized Comparison of the BioFreedomTM Biolomus A9TM Drug coated Stent Versus the GazelleTM Bare Metal Stent in Patients at High Risk for Bleeding

2016

Completed

TRIUS – A Phase 3 Randomized Double-blind Study Comparing TR-701 FA and Linezolid in Ventilated Gram-positive Nosocomial Pneumonia

2016

Completed

MAESTRO DB – A Multi-Center, Double-Blind, Randomized, Placebo- Controlled, Parallel-Group, Phase 3 Study to Evaluate the Effects of Macitentan on Exercise Capacity Subjects with Eisenmenger Syndrome- Protocol number: AC-055-305

2017

Completed

QUALIFY REGISTRY – Quality of Adherence to Guideline Recommendations for Life-Saving Treatment in Heart Failure: an International Survey

2017

Completed

FOURIER – A Double-Blind, Randomized, Placebo-Controlled, Multicenter Study Assessing the Impact of Additional LDL-Cholesterol Reduction on Major Cardiovascular Events When AMG 145 is Used in Combination with Statin Therapy in Patients with Clinically Evident Cardiovascular Disease.

2017

Completed

Relax Asia – A multicenter, Randomized, Double-Blind, Placebo Controlled Phase III Study Efficacy, to Evaluate the Safety and Tolerability of Serelaxin when Added To Standard Therapy in Acute Heart Failure Patients

2017

Completed

MODIFY – Effects of Ivabradine on Plaque Burden, Morphology and Composition in Patients with Clinically Indicated Coronary Angiography. A Randomised Double-Blind Placebo-controlled International Multicentre Study

Completed

SERAPHIN ( Open Label) – Study With Endothelin Receptor Antagonist in Pulmonary Arterial Hypertension to Improve  Clinical Outcome

2018

Completed

PARADIGM-HF Open Label – A Multicenter, Randomized, Double-Blind, Parallel Group, Active-Controlled Study to Evaluate the Efficacy and Safey of LCZ696 Compared to Enalapril on Morbidity and Mortality in Patients With Chronic Heart Failure and Reduced Ejection Fraction.

2018

Completed

NIS RELATE – A Study Where the Medicinal Product(s) is (are) Prescribed in the Usual Manner in Accordance With the Terms of the Marketing Authorization. The Assignment of the Patient to a Particular Therapeutic Strategy is Not Decided in Advance by a Trial Protocol But Falls Within the Current Practice and the Prescription of the Medicine is Clearly Separated From the Decision to Include the Patient in the Study. No Additional Diagnostic or Monitoring Procedures Shall be Applied to the Patients and Epidemiological Methods Shall be Used for the Analysis of the CollectedData

2018

Completed

MASCOT REGISTRY – Multinational Abluminal Sirolimus Coated Bio-Engineered Stent

2018

Completed

COROFLEX ISAR INTERNATIONAL REGISTRY

2018

Completed

TRICS III – Transfusion Requirements in Cardiac Surgery

2018

Completed

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