Marfan syndrome affects the connective tissue in our body. Connective tissue acts like cement, holding the cells, organs and tissues together. In Marfan syndrome and related disorders, this causes anomalies especially in the bone, joints, heart and eyes. It can also affect the blood vessels for example the aorta (main blood vessel arising from the heart supplying the body) causing it to enlarge. This can be life threatening.
Marfan sydrome is a genetic disorder involving a gene known as fibrilin-1. If a parents has Marfan syndrome, there is a high risk of transmission of the disease to the children. However it can also occur in the absence of a family history due to spontaneous mutation.
* For more information about Marfan syndrome – Visit the Marfan Foundation (https://www.marfan.org/about/marfan)
The Marfan syndrome and Aortopathy clinic offers comprehensive cardiac management for patients with Marfan syndrome and other Aortopathies eg Loeys Dietz syndrome.
This clinic is a combine cardiac and genetic clinic.
The aim is to have multidisciplinary team of cardiology and genetic doctors as well as cardiothoracic surgeons to provide: