Industry Sponsored Research

ONGOING

No.	Research Title	Investigator	Status
1	SELEXIPAG – A Prospective, Multicentre, Open Label, Single Arm, Phase 2 Study to Investigate the Safety, Tolerability and Pharmacokinetics of Selexipag in Children with Pulmonary Arterial Hypertention	Dr. Geetha A/P Kandavello @ Kandhavel	Enrollment
2	FIM-IBS – A Prospective, Non-randomized, Open lable, Non-comparative, First-in-Man Study to Evaluate the Feasibility and Safety of Sirolimus-eluting Iron Bioresorbable Coronary Scaffold System	Dr. Shaiful Azmi Yahaya	Enrollment
3	UNIVERSE – A Prospective, Open-Label, Active-Controlled Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Safety, and Efficacy of Rivaroxaban for Thromboprophylaxis in Pediatric Subject 2 to 8 Years of Age after the Fontan Procedure	Dr. Hasri Samion	Enrollment
4	VITALITY-HFpEF – A Randomized Parallel-group, Placebo-controlled, Double-blind, Multi-centre Trial to Evaluate the Efficacy and Safety of the Oral SGC Stimulator Vericiguat to Improve Physical Functioning in Activities of Daily Living in Patients with Heart Failure and Preserved Ejection Fraction	Dr. Teoh Chee Kiang	Enrollment
5	BIOSOLVE -IV – Safety and Performance in de Novo Lesion of NatiVE Coronary Arteries with Magmaris-Registry	Dato’ Dr. Amin Ariff Nuruddin	Enrollment
6	CONSEQUENT ALL COMERS Registry – Clinical Post Market Clinical Follow-Up (PMCF) on Peripheral Arteries treated with Sequent ® Please OTW Paclitaxel Coated Ballon Catheter in an All Comer Patient Population	Dr. Shaiful Azmi Yahya	Enrollment
7	PASSWORD Registry – Post market Surveillance of SeQuent® Please Neo with Scoring Ballon Lesion Preparation in Real World Patients	Datuk Dr. Ahmad Khairuddin Mohamed Yusof	Enrollment
8	MPP – Product Surveillance Registry – Multiple Point Pacing (MPP) Post Approval Study	Dr. Zulkeflee Muhammad	Enrollment

No.	Research Title	Investigator	Status
1	PARADIGM-HF – A Multicenter Study to Evaluate Safety and Tolerability in Patients with Chronic Heart Failure and Reduced Enjection Fraction from PARADIGM-HF receiving Open Label LCZ696	Dr. Ng Yau Piow	Follow Up
2	MeRes – 1 Extend – A Prospective, Multicentre, Single arm, Open label, Pilot Clinical Study of MeRes100 Sirolimus Eluting Bioreorbable Vascular Caffold System in the Treatment of de-novo Native Coronary Artery Lesions	Dato’ Dr. Amin Ariff Nuruddin	Follow Up
3	ASIAN HF – Asian Sudden Cardiac Death in Heart Failure (ASIAN HF) Prospective Observational Registry	Dr. Surinder Kaur Khelae	Follow Up
4	ASQuad – Attain StabilityTM Quad Clinical Study	Dr. Azlan Hussin	Follow Up
5	BIOFLOW-III Registry – Safety and Performance Registry for an all-comers Diabetic patient population with the Limus Eluting Orsiro Stent System within daily clinical practice – III	Dr. Shaiful Azmi Yahaya	Follow Up
6	BIOLUX P-III Registry – A prospective, international, multi-centre, post-market all-comers registry to assess the clinical performance of the Passeo-18 Lux Paclitaxel releasing balloon catheter in infraguinal arteries	Dr. Shaiful Azmi Yahaya	Follow Up
7	ISAR Neo – Coroflex ISAR Neo Registry in Malaysia	Dato’ Dr. Amin Ariff Nuruddin	Follow Up
8	FIM-LIMUS-DCB – Treatment of Coronary in-Stent Restenosis by a Sirolimus (rapamycin) Coated ballon or a Paclitaxel Coated Ballon	Dato’ Dr. Amin Ariff Nuruddin	Follow Up
9	GRIPHON OL – Long Term, single-arm,open-label study, to assess the Safety and tolerability of ACT-293987 in patients with pulmonary arterial hypertension	Dr. Teoh Chee Kiang	Follow Up
10	IMPROVE SCA – A Prospective, Non-Randomized, Non-Blinded, Multi-Site Global Post-Market Study with a Focus in Emerging Markets to Demonstrate that Primary Prevention Patients with Additional Risk Factors (1.5 Risk Factors) are at a Similar Risk of Sudden	Dr. Azlan Hussin	Follow Up
11	ISCHEMIA – International Study of Comparative Health Effectiveness with Medical and Invasive Approaches	Datuk Dr. Ahmad Khairuddin Mohamed Yusof	Follow Up
12	MARVEL – Micra Artial Tracking Using A Venticular AccELerometer (MARVEL) Clinical Research Feasibility study	Dr. Surinder Kaur Khelae	Follow Up
13	Onyx ONE – A Randomized Controlled Trial with Resolute Onyx in One Month DAPT for High-Bleeding Risk Patients	Dato’ Dr. Amin Ariff Bin Nuruddin	Follow Up
14	ACOSYM – Prospective Observational study of Lipid management in South East Asian Patients who have a Recent Acute Coronary Syndrome Event	Dr. Emily Lay Koon Tan	Follow Up
15	XPLORE-1 – Prospective, Non-Randomised, Open-label Clinical Study to Assess the Safety of the Bioabsorbable Pulmonary Valve Conduit (PV-001) in Subjects Undergoing Right Ventricular Outflow Tract (RVOT) Reconstruction	Dato’ Seri Dr. Mohd Azhari Yakub	Follow Up
16	PROTECT-ICD – Programmed Ventricular Stimulation to Risk Stratify for Early Cardioverter-Defibrillator (ICD) Implantation to Prevent Tachyarrhythmias Following Acute Myocardial Infarction	Dr. Surinder Kaur Khelae	Follow Up
17	REDUCE – Randomized Evaluation of short-term DUal anti platelet therapy in patients with acute coronary syndrome treated with the COMBO dual-therapy stEnt	Tan Sri Dato Seri Dr. Robaayah Zambahari	Follow Up
18	REPAIR – Right vEntricular remodeling in Pulmonary ArterIal hypeRtension A prospective, multicenter, single-arm, open-label, Phase 4 study to evaluate the effects of macitentan on Right vEntricular remodeling in Pulmonary ArterIal hypeRtension assessed by cardiac magnetic resonance imaging	Dr. Geetha A/P Kandavello @ Kandhavel	Follow Up
19	SAMURAI – ImageReady™ MR Conditional Pacing System Clinical Study	Dr. Surinder Kaur Khelae	Follow Up
20	WASP Registry – Watchman Asia Pacific Registry	Dr. Zulkeflee Muhammad	Follow Up

COMPLETED